Testosterone therapy is often referred as a dangerous elixir due to its dangerous after-effects. Oral medications included in this hormonal replacement theory are known to cause liver toxicity. It is significant to note that every pack of such oral medications included in the therapy contain a strict warning on the possible liver disorders on the long term usage or wrong dosage of the medicine. The therapy is further known to severely affect the fertility of men. Since the therapy initiates the external production of testosterone, the natural tendency of the testes to release these hormones receives a setback. In this condition the testes stop the production of testosterone absolutely as well as inhibit the production of sperm almost completely.

This leads to a condition called Spermatogenesis which lasts for a temporary period. Further, many men and women experience severe forms of sleep apnea where the individuals find troubles in breathing, especially whilst sleeping. In severe cases, men may experience the enlargement of their breasts which can become a source of great embarrassment. This condition is particularly observed among older men that can be cured by reducing the dosage of testosterone enhancement pills. At last, one of the most dreadful side effects of this therapy is the massive increase in red blood cells in the body. This condition can increase the risk of having heart strokes, clotting and attacks.