Testosterone therapy has a number of side effects. One of them is the elevated risk level for developing prostrate diseases. Count of symptomatic benign prostatic hyperplasia is increased in middle aged men after testosterone therapy. It also adds to prostate carcinoma. The reason behind it is that testosterone therapy has impact on role of androgens. Androgens are the major factors behind all prostate gland diseases. 

 However, the medical fraternity is not unanimous on effect of testosterone therapy on androgens. Some research works have found that this therapy has least impacts on benign prostatic hyperplasia, serum prostate-specific antigen level and vulnerability towards prostate cancer.  However, some doctors are of the view that this therapy can aggravate the chance of prostate related diseases.

 Drugs used to heal treat prostate cancer lower down the testosterone secretion in our body. But, testosterone therapy has negative impact on prostate related disease. Healthy men with undetected prostate cancer have 25% more risk of aggravating the situation after the therapy. The risk factors manifold after the person passes age of fifty.  Hence, if you have disorders at prostate, you should consult doctor before going for testosterone therapy.